{"product_id":"aspirin-direct-500-mg-granules-20-sachets","title":"Aspirin Direct 500 mg granules 20 sachets","description":"\u003cp _msthash=\"99\" _msttexthash=\"10822591\"\u003eAspirin Direkt contains the active ingredient acetylsalicylic acid (ASA). This has an analgesic, antipyretic and anti-inflammatory effect.\u003c\/p\u003e\n\u003cp _msthash=\"100\" _msttexthash=\"145132572\"\u003eWhen is Aspirin Direct used?\u003cbr _istranslated=\"1\"\u003eSymptomatic treatment of mild to moderate pain such as headaches, toothache and menstrual pain.\u003cbr _istranslated=\"1\"\u003eFor the relief of pain and fever in colds and flu-like infections.\u003cbr _istranslated=\"1\"\u003eIf you do not feel better or even worse with pain after 3-4 days and with fever after 3 days, when new symptoms appear (for example, redness or swelling), it is imperative to consult a doctor, as these can be signs of a serious illness.\u003cbr _istranslated=\"1\"\u003eAspirin Direct is used in adults and adolescents over 12 years of age. Please note the information for children (see point 2).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong _msthash=\"101\" _msttexthash=\"352807\"\u003eContraindications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp _msthash=\"102\" _msttexthash=\"536770\"\u003eDo not take Aspirin Direct,\u003c\/p\u003e\n\u003cul\u003e\n\u003cli _msthash=\"103\" _msttexthash=\"9882587\"\u003eif you are allergic to acetylsalicylic acid, other salicylates or to any of the other ingredients of this medicine (listed in section 6);\u003c\/li\u003e\n\u003cli _msthash=\"104\" _msttexthash=\"25556232\"\u003eif you have a history of asthma attacks or otherwise hypersensitive to certain pain-relieving medicines - acetylsalicylic acid or substances with a similar mechanism of action (non-steroidal anti-inflammatory drugs);\u003c\/li\u003e\n\u003cli _msthash=\"105\" _msttexthash=\"1668277\"\u003eif you suffer from acute gastrointestinal ulcers;\u003c\/li\u003e\n\u003cli _msthash=\"106\" _msttexthash=\"14759940\"\u003eif you have a history of bleeding, ulcers or breakthrough in the gastrointestinal tract due to previous therapy with NSAIDs (non-steroidal anti-inflammatory drugs);\u003c\/li\u003e\n\u003cli _msthash=\"107\" _msttexthash=\"11490843\"\u003eif you have active gastrointestinal ulcers\/bleeding or if you have a history of bleeding, ulcers or a breakthrough in the gastrointestinal area;\u003c\/li\u003e\n\u003cli _msthash=\"108\" _msttexthash=\"4604938\"\u003eif you suffer from pathologically increased bleeding tendency (hemorrhagic diathesis);\u003c\/li\u003e\n\u003cli _msthash=\"109\" _msttexthash=\"1347632\"\u003eif you suffer from severe liver dysfunction;\u003c\/li\u003e\n\u003cli _msthash=\"110\" _msttexthash=\"1341080\"\u003eif you suffer from severe renal dysfunction;\u003c\/li\u003e\n\u003cli _msthash=\"111\" _msttexthash=\"1924741\"\u003eif you suffer from severe heart failure (heart failure);\u003c\/li\u003e\n\u003cli _msthash=\"112\" _msttexthash=\"9675445\"\u003eif you are taking 15 mg or more of methotrexate (medicines used to treat cancer or certain rheumatic diseases) per week at the same time;\u003c\/li\u003e\n\u003cli _msthash=\"113\" _msttexthash=\"7681076\"\u003eif you are taking anticoagulants (medicines to \"thin the blood\") at the same time, if high doses of salicylates are used;\u003c\/li\u003e\n\u003cli _msthash=\"114\" _msttexthash=\"768547\"\u003ein the last 3 months of pregnancy.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp _msthash=\"115\" _msttexthash=\"2711098\"\u003eAspirin Direct should not be given to children under one year of age.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong _msthash=\"116\" _msttexthash=\"208845\"\u003eInteractions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp _msthash=\"117\" _msttexthash=\"75310664\"\u003eThe effect of the following drugs or groups of preparations can be influenced by simultaneous treatment with Aspirin Direct.\u003cbr _istranslated=\"1\"\u003eIf you are taking methotrexate (medicines used to treat cancer or certain rheumatic diseases) at doses of 15 mg\/week or more, do not take Aspirin Direct.\u003cbr _istranslated=\"1\"\u003eIf you are taking anticoagulants (medicines to \"thin the blood\"), you must not take Aspirin Direkt in high doses.\u003c\/p\u003e\n\u003cp _msthash=\"118\" _msttexthash=\"1133574\"\u003eCombinations that require special care:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli _msthash=\"119\" _msttexthash=\"14082133\"\u003eMethotrexate at doses below 15 mg\/week (medicines used to treat cancer or certain rheumatic diseases) - there is a risk of increased (side) effects of methotrexate.\u003c\/li\u003e\n\u003cli _msthash=\"120\" _msttexthash=\"164836542\"\u003eAnticoagulant medicines, blood clot-dissolving medicines\/other medicines that inhibit platelets sticking together and clumping together (antiplatelet agents)\/medicines to inhibit hemostasis (haemostasis inhibitors) - bleeding can occur due to increased action. Aspirin Direct may increase the risk of bleeding if taken before a treatment designed to dissolve blood clots. Therefore, you need to pay close attention to signs of external or internal bleeding (for example, bruising) if you are to undergo such treatment. A medical check-up is absolutely necessary.\u003c\/li\u003e\n\u003cli _msthash=\"121\" _msttexthash=\"33722481\"\u003eOther analgesic and anti-inflammatory drugs (non-steroidal anti-inflammatory drugs\/anti-inflammatory drugs) at high doses of acetylsalicylic acid: increased risk of ulcers and bleeding in the gastrointestinal tract; an overdose is also possible.\u003c\/li\u003e\n\u003cli _msthash=\"122\" _msttexthash=\"12545091\"\u003eCertain medicines used to treat depression (selective serotonin reuptake inhibitors): the risk of bleeding in the gastrointestinal tract increases.\u003c\/li\u003e\n\u003cli _msthash=\"123\" _msttexthash=\"40174264\"\u003eCertain medicines for the treatment of cardiac insufficiency and for the treatment of certain cardiac arrhythmias (digoxin): Enhancement of the effect up to increased risk of side effects. Appropriate monitoring and, if necessary, dose adjustment by the doctor is recommended.\u003c\/li\u003e\n\u003cli _msthash=\"124\" _msttexthash=\"13259051\"\u003eCertain medicines for gout (eg, probenecid, benzbromarone). Weakening of the effect of gout remedies possible. It is recommended to use another painkiller.\u003c\/li\u003e\n\u003cli _msthash=\"125\" _msttexthash=\"14296685\"\u003eMedicines for diabetes (e.g. insulin, sulfonylureas): hypoglycaemia can occur due to increased effect. More frequent blood glucose self-checks are recommended.\u003c\/li\u003e\n\u003cli _msthash=\"126\" _msttexthash=\"55465930\"\u003eCertain medicines for dehydration and lowering blood pressure (diuretics): there is a risk of severe renal dysfunction. When taken at the same time, it is important to ensure sufficient fluid intake. Certain dehydrating agents (e.g. furosemide) may weaken the antihypertensive effect, so blood pressure checks are recommended.\u003c\/li\u003e\n\u003cli _msthash=\"127\" _msttexthash=\"39300456\"\u003eMedicines containing cortisone or cortisone-like substances (with the exception of products applied to the skin or hydrocortisone in cortisone replacement therapy for Addison's disease): increased risk of side effects (bleeding or ulcers) in the gastrointestinal tract.\u003c\/li\u003e\n\u003cli _msthash=\"128\" _msttexthash=\"64922637\"\u003eCertain medicines for high blood pressure (antihypertensives) and\/or cardiac insufficiency (\"ACE inhibitors\", aldosterone antagonists): there is a risk of severe renal dysfunction and the antihypertensive effect may also be reduced. When taken at the same time, it is important to ensure sufficient fluid intake. Blood pressure checks are recommended.\u003c\/li\u003e\n\u003cli _msthash=\"129\" _msttexthash=\"6460987\"\u003eCertain medicines for epilepsy (valproic acid): There is a risk of increased (side) effects of valproic acid.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp _msthash=\"130\" _msttexthash=\"11671530\"\u003ePlease also note that:\u003cbr _istranslated=\"1\"\u003eAspirin Direct in higher doses may alter the results of laboratory tests, so inform your doctor about taking Aspirin Direct.\u003c\/p\u003e\n\u003cp _msthash=\"131\" _msttexthash=\"31399121\"\u003eTaking Aspirin Direct together with alcohol\u003cbr _istranslated=\"1\"\u003ePlease avoid drinking alcohol during the treatment period with Aspirin Direct, it could increase the side effects of the drug (risk of bleeding in the gastrointestinal tract, prolonged bleeding time).\u003c\/p\u003e\n\u003cp _msthash=\"132\" _msttexthash=\"23346817\"\u003ePregnancy, breastfeeding and reproductive function\u003cbr _istranslated=\"1\"\u003eIf you are pregnant or breastfeeding, or if you think you may be pregnant or intend to become pregnant, ask your doctor for advice before taking this medicine.\u003c\/p\u003e\n\u003cp _msthash=\"133\" _msttexthash=\"276431766\"\u003ePregnancy:First and second trimester of pregnancy:\u003cbr _istranslated=\"1\"\u003eDuring the first six months of pregnancy and if you want to have children,\u003cbr _istranslated=\"1\"\u003eyou should only take Aspirin Direkt after consulting your doctor. The aim is to keep the dose low and the treatment as short as possible.\u003cbr _istranslated=\"1\"\u003eThird trimester of pregnancy: In the last three months of pregnancy,\u003cbr _istranslated=\"1\"\u003eyou must not take Aspirin Direkt because of an increased risk of complications for both mother and baby.\u003cbr _istranslated=\"1\"\u003eDue to the acetylsalicylic acid component, there is a risk of developmental disorders in the unborn child (malformations in the circulatory system and\/or renal dysfunction up to kidney failure).\u003cbr _istranslated=\"1\"\u003eDuring childbirth, there may be increased bleeding in mother and child and delay\/prolongation of the birth process.\u003c\/p\u003e\n\u003cp _msthash=\"134\" _msttexthash=\"55470818\"\u003eLactation:\u003cbr _istranslated=\"1\"\u003eThe active ingredient acetylsalicylic acid and its degradation products are excreted in breast milk in small quantities. With short-term use of Aspirin Direct and low dose, interruption of breastfeeding will not be necessary. However, if you use or take high doses for a longer period of time, you should stop weaning.\u003c\/p\u003e\n\u003cp _msthash=\"135\" _msttexthash=\"26231699\"\u003eReproductive function:\u003cbr _istranslated=\"1\"\u003eAspirin Direct belongs to a group of medicines (non-steroidal anti-inflammatory drugs) that can affect women's fertility. This effect is reversible (reversible) after discontinuation of the drug.\u003c\/p\u003e\n\u003cp _msthash=\"136\" _msttexthash=\"132114983\"\u003eAspirin Direct contains aspartame and sodium\u003cbr _istranslated=\"1\"\u003eThis medicine contains 5 mg of aspartame per sachet as a source of phenylalanine. It can be harmful if you have phenylketonuria (PKU), a rare congenital condition in which phenylalanine builds up because the body can't break it down sufficiently.\u003cbr _istranslated=\"1\"\u003eThis medicinal product contains 19 mg (1 sachet) or 38 mg (2 sachets) of sodium (the main ingredient in table salt). This corresponds to 0.95% and 1.9% of the maximum daily dietary sodium intake recommended for an adult, respectively\u003c\/p\u003e\n\u003cp\u003e\u003cstrong _msthash=\"137\" _msttexthash=\"180544\"\u003eApplication\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp _msthash=\"138\" _msttexthash=\"26626548\"\u003eAlways take Aspirin Direkt exactly as described in this leaflet or exactly as your doctor has told you. Please check with your doctor or pharmacist if you are unsure.\u003cbr _istranslated=\"1\"\u003eUnless otherwise prescribed by the doctor, the usual dose is:\u003c\/p\u003e\n\u003cp _msthash=\"139\" _msttexthash=\"107770377\"\u003eAge: Adults and adolescents aged 12 and\u003cbr _istranslated=\"1\"\u003eover Single dose: 1–2 sachets of granules (equivalent to 500 mg – 1000 mg acetylsalicylic acid)Total daily dose: 3 – maximum 6 sachets of granules (equivalent to 1500 – 3000 mg acetylsalicylic acid) The maximum daily dose of 6 sachets of granules (equivalent to 3000 mg acetylsalicylic acid)\u003cbr _istranslated=\"1\"\u003emust not be exceeded.\u003c\/p\u003e\n\u003cp _msthash=\"140\" _msttexthash=\"39074243\"\u003eUse in children under 12 years of age:\u003cbr _istranslated=\"1\"\u003eMedicines containing ASA (such as aspirin direct) should only be given to children under 12 years of age with a doctor's prescription.\u003cbr _istranslated=\"1\"\u003eAspirin Direkt is not suitable for children, as children's dosages are not possible with this dosage form.\u003c\/p\u003e\n\u003cp _msthash=\"141\" _msttexthash=\"29729856\"\u003eMethod of administration For oral use\u003cbr _istranslated=\"1\"\u003e.\u003cbr _istranslated=\"1\"\u003ePut Aspirin Direct granules in the mouth directly on the tongue. The granules dissolve in saliva and can then be swallowed. If desired, some liquid can be drunk afterwards.\u003cbr _istranslated=\"1\"\u003eDo not take on an empty stomach.\u003c\/p\u003e\n\u003cp _msthash=\"142\" _msttexthash=\"125325616\"\u003eDuration of use\u003cbr _istranslated=\"1\"\u003eThe single dose, if necessary, can be taken at intervals of 4-8 hours up to 3 times a day.\u003cbr _istranslated=\"1\"\u003eHowever, the total daily dose of a maximum of 6 sachets of granules must not be exceeded.\u003cbr _istranslated=\"1\"\u003eAspirin Direct can be taken for no more than 3-4 days in case of pain and no more than 3 days in case of fever without a doctor's order. If pain or fever persists during this time, or even gets worse when new symptoms appear (such as redness or swelling), you need to see your doctor, as these may be signs of a serious illness.\u003c\/p\u003e\n\u003cp _msthash=\"143\" _msttexthash=\"321127066\"\u003eSpecial patient groups:Elderly people (65 years of age and older) and underweight people:\u003cbr _istranslated=\"1\"\u003e\u003cbr _istranslated=\"1\"\u003eIn elderly patients, special caution should be exercised due to possible comorbidities or underweight (see sections \"Do not take Aspirin Direct\" and \"Warnings and precautions\"). In particular, it is recommended to use the lowest effective dose in the elderly and underweight.\u003cbr _istranslated=\"1\"\u003ePatients with hepatic impairment:\u003cbr _istranslated=\"1\"\u003eIf they suffer from hepatic impairment, the dose must be reduced or the interval between two doses must be extended. In case of severe liver dysfunction, you must not take Aspirin Direct.\u003cbr _istranslated=\"1\"\u003ePatients with renal impairment:\u003cbr _istranslated=\"1\"\u003eIf you suffer from renal impairment, the dose must be reduced or the interval between two doses must be extended. In case of severe renal dysfunction, you must not take Aspirin Direct.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong _msthash=\"144\" _msttexthash=\"178126\"\u003eSide effects\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp _msthash=\"145\" _msttexthash=\"4815694\"\u003eLike all medicines, this medicine can cause side effects, although not everybody gets them.\u003c\/p\u003e\n\u003cp _msthash=\"146\" _msttexthash=\"3886181\"\u003eThe following side effects are possible and listed according to their frequency:\u003c\/p\u003e\n\u003cp _msthash=\"147\" _msttexthash=\"8196591\"\u003eCommon (may affect up to 1 in 10 people): gastrointestinal\u003cbr _istranslated=\"1\"\u003ecomplaints such as heartburn, nausea, vomiting, abdominal pain.\u003c\/p\u003e\n\u003cp _msthash=\"148\" _msttexthash=\"11067602\"\u003eUncommon (may affect up to 1 in 100 people):\u003cbr _istranslated=\"1\"\u003eHypersensitivity reactions, such as skin reactions.\u003cbr _istranslated=\"1\"\u003eRedness of the skin, hives (urticaria), itching.\u003c\/p\u003e\n\u003cp _msthash=\"149\" _msttexthash=\"361726144\"\u003eRare (may affect up to 1 in 1,000 people):\u003cbr _istranslated=\"1\"\u003eHypersensitivity reactions of the respiratory, gastrointestinal and cardiovascular systems, especially in asthma patients. Signs of a hypersensitivity reaction may include: drop in blood pressure, bouts of shortness of breath, runny nose, nasal congestion, life-threatening shock or swelling of the skin and mucous membrane.\u003cbr _istranslated=\"1\"\u003eSevere skin reactions such as rash with redness, blistering and peeling of the skin.\u003cbr _istranslated=\"1\"\u003eGastrointestinal inflammation, gastrointestinal ulcers, gastrointestinal bleeding, which very rarely can lead to anemia due to iron deficiency.\u003cbr _istranslated=\"1\"\u003eBreakthrough of a gastrointestinal ulcer, especially in elderly patients. In case of abdominal pain, blackening of the stool, vomiting of blood or vomiting like coffee grounds, discontinue aspirin directly and inform the doctor immediately.\u003c\/p\u003e\n\u003cp _msthash=\"150\" _msttexthash=\"35415406\"\u003eRare to very rare:\u003cbr _istranslated=\"1\"\u003eSerious haemorrhages such as cerebral haemorrhage, especially in patients with uncontrolled hypertension and\/or concomitant treatment with anticoagulant medicines, have been reported, which can be life-threatening in individual cases.\u003c\/p\u003e\n\u003cp _msthash=\"151\" _msttexthash=\"24839737\"\u003eVery rare (may affect up to 1 in 10,000 people):\u003cbr _istranslated=\"1\"\u003edrop in blood sugar.\u003cbr _istranslated=\"1\"\u003eAcetylsalicylic acid reduces uric acid excretion in low doses. In patients at risk for this, this can trigger a gout attack under certain circumstances.\u003c\/p\u003e\n\u003cp _msthash=\"152\" _msttexthash=\"1399801403\"\u003eNot known (frequency cannot be estimated from the available data):\u003cbr _istranslated=\"1\"\u003eAnemia due to blood loss or decay, decay of red blood cells.\u003cbr _istranslated=\"1\"\u003eDrug hypersensitivity, allergic swelling and swelling of the skin and mucous membrane, severe allergic reaction up to life-threatening shock.\u003cbr _istranslated=\"1\"\u003eCerebral hemorrhage and cranial hemorrhage.\u003cbr _istranslated=\"1\"\u003eDizziness, headaches, impaired hearing, ringing in the ears and mental confusion can already be signs of an overdose.\u003cbr _istranslated=\"1\"\u003eShortness of breath caused by heart disease.\u003cbr _istranslated=\"1\"\u003eBleeding with prolonged bleeding time such as nosebleeds, bleeding gums, skin bleeding, bleeding of the urinary and genital organs (genitourinary tract), bleeding both during and after surgery, bruising or muscle bleeding. This effect can last for 4 to 8 days after stopping taking Aspirin Direct.\u003cbr _istranslated=\"1\"\u003eAsthma, runny nose, nasal congestion.\u003cbr _istranslated=\"1\"\u003eIndigestion, pain in the gastrointestinal tract, pain in the upper abdomen.\u003cbr _istranslated=\"1\"\u003eLiver dysfunction, increases in liver function tests. Sudden, regressive severe hepato-damaging episodes have been reported, particularly in patients with a history of liver damage and in rheumatism patients, such as those with juvenile arthritis, rheumatic fever or systemic lupus erythematosus. (In these patients, the doctor will check liver function regularly). Restriction of renal function, acute renal failure.\u003cbr _istranslated=\"1\"\u003eSwelling due to water retention in tissues, hypertension and heart failure have been reported in association with nonsteroidal anti-inflammatory drugs (NSAIDs) treatment.\u003cbr _istranslated=\"1\"\u003eThe use of medicines such as Aspirin Direct may be associated with a slightly increased risk of suffering a heart attack or stroke (especially at high doses and as part of long-term treatment).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong _msthash=\"153\" _msttexthash=\"185497\"\u003eComposition\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp _msthash=\"154\" _msttexthash=\"6870916\"\u003eThe active ingredient is acetylsalicylic acid. 1 sachet of granules contains 500 mg of acetylsalicylic acid (ASA).\u003c\/p\u003e\n\u003cul\u003e\n\u003cli _msthash=\"155\" _msttexthash=\"12402091\"\u003eThe other ingredients are mannitol, sodium bicarbonate, sodium dihydrogen citrate, ascorbic acid, cola flavor, orange flavor, citric acid, aspartame.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eUsually ships out within 3-4 days\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Dr. Gepo","offers":[{"title":"Default Title","offer_id":54934974890327,"sku":null,"price":44.67,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1046\/0918\/6135\/files\/12457.png?v=1788804845","url":"https:\/\/drgepo.com\/products\/aspirin-direct-500-mg-granules-20-sachets","provider":"Dr. Gepo","version":"1.0","type":"link"}